Droplet counter-current chromatography of indole alkaloids from Tabernaemontana hilariana
نویسندگان
چکیده
منابع مشابه
Application of preparative high-speed counter-current chromatography for the separation of two alkaloids from the roots of Tabernaemontana catharinensis (Apocynaceae).
The methanolic extract of Tabernaemontana catharinensis (Apocynaceae) roots, which contains alkaloids with several biological activities, was separated on a preparative scale using high-speed counter-current chromatography. The optimum solvent system was found to be a mixture of CHCl(3)-MeOH-H(2)O [5:10:6 (v/v/v)] and led to a successful separation of two monoterpenic indole alkaloids, voachalo...
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Ten indole alkaloids from the chloroform extract of stalk of Tabernaemontana australis (Muell. Arg) Miers were tentatively identified by GC-MS, viz., coronaridine (1), voacangine (2), voacangine hydroxyindolenine (3), rupicoline (4), ibogamine (5), ibogaine (6), ibogaline (7), desethyl-voacangine (8), voachalotine (9), and affinisine (10). Of these, the first four were isolated by silica gel op...
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Leishmaniasis is a parasitic infection that is considered worldwide one of the most important public health problem, affecting more than 12 million people with an estimated number of 2 million new cases occurring annually. Among the compounds isolated from Tabernaemontana catharinensis, coronaridine and voacangine are the indole alkaloids which have antileishmanial activity. In this work, the t...
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The aim of this paper was to seek an efficient method to preparative separation of alkaloid compounds from Aconitum coreanum (Guanbaifu), a well-known traditional Chinese medicinal plant for heart disease. Seven alkaloid compounds were successfully purified by pH-zone-refining counter-current chromatography with two-phase solvent system of petroleum ether-ethyl acetate-methanol-water (5:5:1:9, ...
متن کاملPurification of Sesquiterpenes from Saussurea LappaRoots by High Speed Counter Current Chromatography
Sesquiterpenes lactones including costunolide and dehydrocostus lactone, were isolated from Saussurea lappa roots, which had exhibited a wide range of biological activities such as anti-cancer, anti-inflammatory, antiulcer, and immunomodulatory activities. High-speed counter-current chromatography (HSCCC) was applied for the rapid preparative isolation of sesquiterpenes lactones from <...
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ژورنال
عنوان ژورنال: Phytochemical Analysis
سال: 1999
ISSN: 0958-0344,1099-1565
DOI: 10.1002/(sici)1099-1565(199903/04)10:2<60::aid-pca446>3.0.co;2-y